Author : Nagajyothi M 1
Date of Publication :16th August 2017
Abstract: One of the applications that use nanosecond and subnanosecond high voltage pulses is cancer therapy. In particular , non-thermal changes in the cells, especially the permeabilization of the membrane can be introduced using subnanosecond pulses. The motivation is to radiate intense subnanosecond pulses to the tumors non-invasively. Intense EM waves that is emitted at the first focal point is been focused at the second focal point where the target that is the tumor is present. Two antennas with PSR are designed to focus pulsed type field at the second focal point. The modified bicone antenna and elliptically tapered horn antenna as feeds for PSR is designed. Comparison of design parameters and radiation performance is done.
Reference :
-
[1] Design of compact electromagnetic impuls radiating antenna for melanoma treatment. Petrishia Arockiasamy and Sasikala Mohan
[2] Electronics and Communication, Department of ECE, College of Engineering, Anna University, Chennai, India
[3] Nuccitelli, R., Pliquett, U., Chen, X., et al. (2006). Nanosecond pulsed electric fields cause melanomas to self-destruct. Biochem. Biophys. Res. Commun. 343:351–360. Schoenbach, K. H., Hargrave, B., Joshi, R. P., et al. (2007). Bioelectriceffects of intense nanosecond pulses. IEEE Trans. Dielectr. Electr. Insul. 14:1088–1119..
[4] Schoenbach, K. H., Xiao, S., Joshi, R. P., et al. (2008). The effect of intense subnanosecond electrical pulses on biological cells. IEEE Trans. Plasma Sci. 36:414–422.
[5] Desrumaux, L., Godard, A., Lalande, M., et al. (2010). An original antenna for transient high power UWB arrays: The shark antenna. IEEE Trans. Anten. Propag. 5
[6] Diot, J. C., Delmote, P., Andrieu, J., et al. (2007). A novel ultra-wide band antenna for transient UWB applications in the frequency band 300 MHz–3 GHz: The valentine antenna. IEEE Trans. Anten. Propag. 55:987–990.
[7] Ghosh, D., De, A., Taylor, M. C., et al. (2006). Transmission and reception by ultra wideband (UWB) antennas. IEEE Trans. Antennas Propag. 48:67–99.