Author : Mr. Imran Shaikh 1
Date of Publication :28th February 2022
Abstract: Liver cancer detection using the computer vision methods and machine learning already received significant attention of researchers for authentic diagnosis and on-time medical attentions. The Computer Aided Diagnosis (CAD) preferred for cancer detection all over the world which is based on image processing service. Earlier CAD tools were designed using conventional machine learning techniue using semi-automatic approach. The modern growth of deep learning for automatic detection and classification leads to significant improvement in accuracy. This paper the automatic CAD framework for liver cancer detection using Convolutional Neural Network (CNN) including Long Short Term Memory (LSTM). The input Computed Tomography (CT) scan images early pre-processed for quality enhancement. After that we applied the lightweight and accuracy field of Interest (ROI) extraction technique using dynamic binary segmentation. From ROI images, we extracted automated CNN-based appearance and hand-craft features. The consolidation of both features formed unique feature set for classification purpose. The LSTM block is then achieve the classification either into normal or diseased CT image. The CNN-LSTM model is designed in this paper to complement the accuracy of liver cancer detection compared to other deep learning solutions. The experimental results of proposed design using CNN-based features and hybrid hand craft features outperformed the recent state-of-art methods
Reference :
-
- ​​​Nader H. Abdel-massieh, Mohiy M. Hadhoud, Khalid M. Amin, "A Novel Fully Automatic Technique for Liver Tumor Segmentation from CT Scans with knowledge-based constraints", 2010 10th International Conference on Intelligent Systems Design & Applications
- Zhang, Xing & Tian, Jie & Deng, Kexin & Wu, Yongfang & Li, Xiuli. (2010). Automatic Liver Segmentation Using a Statistical Shape Model With Optimal Surface Detection. IEEE transactions on bio-medical engineering. 57. 2622-6. 10.1109/TBME.2010.2056369.
- Hsu, WT, Yeh, JR, Chang, YC, et al. A computer aided for image processing of computed tomography in hepatocellular carcinoma. In: 2011 IEEE international conference on bioinformatics & biomedicine workshops, BIBMW 2011, Atlanta, GA, 12–15 November 2011, pp.942–944. New York: IEEE.
- C. Liu, Y. Huang, J. A. Ozolek, M. G. Hanna, R. Singh & G. K. Rohde, "SetSVM: An Approach to Set Classification in Nuclei-Based Cancer Detection," in IEEE Journal of Biomedical & Health Informatics, vol. 23, no. 1, pp. 351-361, Jan. 2019, doi: 10.1109/JBHI.2018.2803793.
- A. F. Abdulgani & M. Al Ahmad, "Label-Free Normal & Cancer Cells Classification Combining Prony’s Method & Optical Techniques," in IEEE Access, vol. 8, pp. 32882-32890, 2020, doi: 10.1109/ACCESS.2020.2973468.
- Ba Alawi A.E., Saeed A.Y.A., Radman B.M.N., Alzekri B.T. (2021) A Comparative Study on Liver Tumor Detection Using CT Images. In: Saeed F., Mohammed F., Al-Nahari A. (eds) Innovative Systems for Intelligent Health Informatics. IRICT 2020. Lecture Notes on Data Engineering & Communications Technologies, vol 72. Springer, Cham. https://doi.org/10.1007/978-3-030-70713-2_14.
- V.Kannan, V.Jagan Naveen 2020. Detection of Liver Cancer Using Image Segmentation . International Journal of Advanced Science & Technology. 29, 3 (Apr. 2020), 7067 - 7078.
- Todoroki Y., Han XH., Iwamoto Y., Lin L., Hu H., Chen YW. (2018) Detection of Liver Tumour Candidates from CT Images Using Deep Convolutional Neural Networks. In: Chen YW., Tanaka S., Howlett R., Jain L. (eds) Innovation in Medicine & Healthcare 2017. KES-InMed 2018 2017. Smart Innovation, Systems & Technologies, vol 71. Springer, Cham. https://doi.org/10.1007/978-3-319-59397-5_15.
- Wang, J., Xu, Z., Pang, ZF. et al. Tumour detection for whole slide image of liver based on patch-based convolutional neural network. Multimed Tools Appl (2020). https://doi.org/10.1007/s11042-020-09282-x.
- E. Trivizakis et al., "Extending 2-D Convolutional Neural Networks to 3-D for Advancing Deep Learning Cancer Classification With Application to MRI Liver Tumour Differentiation," in IEEE Journal of Biomedical & Health Informatics, vol. 23, no. 3, pp. 923-930, May 2019, doi: 10.1109/JBHI.2018.2886276.
- Eugene Vorontsov, Milena Cerny, Philippe Regnier, Lisa Di Jorio, Christopher J. Pal, Real Lapointe, et al., "Deep Learning for Automated Segmentation of Liver Lesions at CT in Patients with Colorectal Cancer Liver Metastases", Radiology: Artificial Intelligence, vol. 1, no. 2, Mar 2019.
- Nadja Gruber, Stephan Antholzer, Werner Jaschke, Christian Kremser & Markus Haltmeier, "A Joint Deep Learning Approach for Automated Liver & Tumour Segmentation", Computer Vision & Pattern Recognition, 2019.
- Amita Dasa U, Rajendra Achary, S.Panda Soumya & Sukanta Sabut, "Deep learning based liver cancer detection using watershed transform & Gaussian mixture model techniques", Cognitive Systems Research Elsevier, vol. 54, pp. 165-175, May 2019.
- Umit Budak, Yanhui Guo, Erkan Tanyildizi & Abdulkadir Sengur, "Cascaded deep convolutional encoder-decoder neural networks for efficient liver tumor segmentation", Medical Hypotheses, vol. 134, pp. 109431, January 2020.
- C. Sun, A. Xu, D. Liu, Z. Xiong, F. Zhao & W. Ding, "Deep Learning-Based Classification of Liver Cancer Histopathology Images Using Only Global Labels," in IEEE Journal of Biomedical & Health Informatics, vol. 24, no. 6, pp. 1643-1651, June 2020, doi: 10.1109/JBHI.2019.2949837.
- E. Trivizakis et al., "Extending 2-D Convolutional Neural Networks to 3-D for Advancing Deep Learning Cancer Classification With Application to MRI Liver Tumor Differentiation," in IEEE Journal of Biomedical & Health Informatics, vol. 23, no. 3, pp. 923-930, May 2019, doi: 10.1109/JBHI.2018.2886276.
- X. Dong, Y. Zhou, L. Wang, J. Peng, Y. Lou & Y. Fan, "Liver Cancer Detection Using Hybridized Fully Convolutional Neural Network Based on Deep Learning Framework," in IEEE Access, vol. 8, pp. 129889-129898, 2020, doi: 10.1109/ACCESS.2020.3006362
- L. Balagourouchetty, J. K. Pragatheeswaran, B. Pottakkat & G. Ramkumar, "GoogLeNet-Based Ensemble FCNet Classifier for Focal Liver Lesion Diagnosis," in IEEE Journal of Biomedical & Health Informatics, vol. 24, no. 6, pp. 1686-1694, June 2020, doi: 10.1109/JBHI.2019.2942774.
- Zhen, S., Cheng, M., Tao, Y., Wang, Y., Juengpanich, S., Jiang, Z., … Cai, X. (2020). Deep Learning for Accurate Diagnosis of Liver Tumor Based on Magnetic Resonance Imaging & Clinical Data. Frontiers in Oncology, 10. doi:10.3389/fonc.2020.00680
- Azer S. A. (2019). Deep learning with convolutional neural networks for identification of liver masses & hepatocellular carcinoma: A systematic review. World journal of gastrointestinal oncology, 11(12), 1218–1230. https://doi.org/10.4251/wjgo.v11.i12.1218.
- Chen, M., Zhang, B., Topatana, W. et al. Classification & mutation prediction based on histopathology H&E images in liver cancer using deep learning. npj Precis. Onc. 4, 14 (2020). https://doi.org/10.1038/s41698-020-0120-3.
- ATSADU, O. ., TANGCHITWILAIKUN, P. ., & LOWSUWANKUL, S. . (2021). Liver Cancer Patient Classification on a Multiple-Stage using Hybrid Classification Methods. Walailak Journal of Science & Technology (WJST), 18(10), Article 9169 (14 pages). https://doi.org/10.48048/wjst.2021.9169.
- Ayalew, Y.A., Fante, K.A. & Mohammed, M. Modified U-Net for liver cancer segmentation from computed tomography images with a new class balancing method. BMC biomed eng 3, 4 (2021).
- Yang, B., Zhang, B., Xu, Y. et al. Prospective study of early detection for primary liver cancer. J Cancer Res ClinOncol123, 357–360 (1997). https://doi.org/10.1007/BF01438313.
- Yoshida, H., Yoshida, H., Shiina, S. et al. Early liver cancer: concepts, diagnosis, and management. Int J ClinOncol10, 384–390 (2005). https://doi.org/10.1007/s10147-005-0537-2. [26] Donato, F., Gelatti, U., Chiesa, R. et al. A case–control study on family history of liver cancer as a risk factor for hepatocellular carcinoma in North Italy. Cancer Causes Control10, 417–421 (1999). https://doi.org/10.1023/A:1008989103809.
- Llovet, J.M. Treatment of hepatocellular carcinoma. Curr Treat Options Gastro7, 431–441 (2004). https://doi.org/10.1007/s11938-004-0002-8.
- Badura P., Pietka E. (2012) 3D Fuzzy Liver Tumour Segmentation. In: Piętka E., Kawa J. (eds) Information Technologies in Biomedicine. Lecture Notes in Computer Science, vol 7339. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-31196-3_5.
- Pan, Q., Zhang, L., Xia, L., Wang, H., and Li, H., “Liver tumour segmentation based on level set”, in Tenth International Conference on Digital Image Processing (ICDIP 2018), 2018, vol. 10806. doi:10.1117/12.2502810
- M. Rela, N. R. Suryakari and P. R. Reddy, "Liver Tumour Segmentation and Classification: A Systematic Review," 2020 IEEE-HYDCON, Hyderabad, India, 2020, pp. 1-6, doi: 10.1109/HYDCON48903.2020.9242757.
- AkifDogantekin, FatihOzyurt, EnginAvci and Mustafa Koc, "A novel approach for liver image classification: PH-C-ELM", Measurement, vol. 137, pp. 332-338, April 2019.
- Ahmed M. Anter and Aboul Ella Hassenian, "Computational intelligence optimization approach based on particle swarm optimizer and neutrosophic set for abdominal CT liver tumour segmentation", Journal of Computational Science Elsevier, vol. 25, pp. 376-387, March 2018.
- Ahmed M. Anter and Aboul Ella Hassenian, "CT liver tumour segmentation hybrid approach using neutrosophic sets fast fuzzy c-means and adaptive watershed algorithm", Artificial Intelligence in Medicine Elsevier, vol. 97, pp. 105-117, June 2019.
- Chin-Chen Chang, Hong-Hao Chen, Yeun-Chung Chang, Ming-Yang Yang, hung-Ming Lo, Wei-Chun Ko, et al., "Computer-aided diagnosis of liver tumours on computed tomography images", Computer Methods and Programs in Biomedicine Elsevier, vol. 145, pp. 45-51, July 2017.
- Zhihua Liu, Long Chen, Lei Tong et.al. “Deep Learning Based Brain Tumour Segmentation: A Survey,” Electrical Engineering and Systems Science, Image and Video Processing, 21 Jul 2020.
- Todoroki Y., Han XH., Iwamoto Y., Lin L., Hu H., Chen YW. (2018) Detection of Liver Tumour Candidates from CT Images Using Deep Convolutional Neural Networks. In: Chen YW., Tanaka S., Howlett R., Jain L. (eds) Innovation in Medicine and Healthcare 2017. KES-InMed 2018 2017. Smart Innovation, Systems and Technologies, vol 71. Springer, Cham.
- Wang, J., Xu, Z., Pang, ZF. et al.Tumour detection for whole slide image of liver based on patch-based convolutional neural network. Multimed Tools Appl (2020) https://doi.org/10.1007/s11042-020-09282-x.
- E. Trivizakiset al., "Extending 2-D Convolutional Neural Networks to 3-D for Advancing Deep Learning Cancer Classification With Application to MRI Liver Tumour Differentiation," in IEEE Journal of Biomedical and Health Informatics, vol. 23, no. 3, pp. 923-930, May 2019, doi: 10.1109/JBHI.2018.2886276.
- Eugene Vorontsov, Milena Cerny, Philippe Regnier, Lisa Di Jorio, Christopher J. Pal, Real Lapointe, et al., "Deep Learning for Automated Segmentation of Liver Lesions at CT in Patients with Colorectal Cancer Liver Metastases", Radiology: Artificial Intelligence, vol. 1, no. 2, Mar 2019.
- Nadja Gruber, Stephan Antholzer, Werner Jaschke, Christian Kremser and Markus Haltmeier, "A Joint Deep Learning Approach for Automated Liver and Tumour Segmentation", Computer Vision and Pattern Recognition, 2019.
- AmitaDasa U, RajendraAchary, S.PandaSoumya and SukantaSabut, "Deep learning based liver cancer detection using watershed transform and Gaussian mixture model techniques", Cognitive Systems Research Elsevier, vol. 54, pp. 165-175, May 2019.
- UmitBudak, YanhuiGuo, ErkanTanyildizi and AbdulkadirSengur, "Cascaded deep convolutional encoder-decoder neural networks for efficient liver tumor segmentation", Medical Hypotheses, vol. 134, pp. 109431, January 2020.
- Dong, X., Zhou, Y., Wang, L., Peng, J., Lou, Y., & Fan, Y. (2020). Liver Cancer Detection using Hybridized Fully Convolutional Neural Network based on Deep learning framework. IEEE Access, 1–1. doi:10.1109/access.2020.3006362.
- Mahajan, H.B., Badarla, A. &Junnarkar, A.A. (2020). CL-IoT: cross-layer Internet of Things protocol for intelligent manufacturing of smart farming. J Ambient Intell Human Comput. https://doi.org/10.1007/s12652-020-02502-0.
- Mahajan, H.B., &Badarla, A. (2018). Application of Internet of Things for Smart Precision Farming: Solutions and Challenges. International Journal of Advanced Science and Technology, Vol. Dec. 2018, PP. 37